15th CEMS Colloquium

講演者

野地博行 (東京大学教授)

日程

2014年3月12日(水) 17:30～18:30

開催場所

理化学研究所　大河内記念ホール

講演タイトル

回転分子モーターATP合成酵素の１分子生物物理

講演概要

The unique feature of ATP synthase that distinguishes from other molecular motor proteins is high reversibility of chemo-mechanical coupling reaction; when the mechanical motion of ATP synthase, that is rotation of the innersubunit complex, is reversed, chemical reaction is also reversed, synthesizing adenosine triphosphate (ATP) from adenosine diphosphate (ADP) and inorganic phosphate against the large chemical potential of ATP hydrolysis. In this presentation, I will introduce our single-molecule experiments conducted with an aim to elucidate how catalytic reaction is coupled with mechanical rotation in ATP synthase. I also like to discuss the prospectives of molecular machine-based technology for highly efficient energy conversion.